Sabouraud Fluid Medium is employed in sterility test procedures for determining the presence of molds, yeasts and aciduric microorganisms. Sabouraud Fluid Medium is also used in the sterility tests of pharmaceutical products, in special parenterals, such as antisera, antibiotic preparations, venipuncture equipment, and saline and glucose solutions. It is recommended in the USP for the determination of the fungistatic activity of pharmaceutical and cosmetic products to prevent false sterility tests. Dextrose is the fermentable carbohydrate providing carbon and energy. Casein and meat peptone provide nitrogen, vitamins, minerals and amino acids essential for growth. The acidic pH of the final medium is inhibitory to a large number of bacteria and makes the medium particularly well-suited for cultivating fungi and acidophilic microorganisms.
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